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Norgine in 2016


            Key highlights





                                Norgine brings transformative products to market which might not                                   Everyone is valued and empowered
                                otherwise be available to patients in Europe, Australia and New Zealand                            to contribute to Vision 2020



                                                       Specialist products portfolio

                                                                                   Cancer and
                                           MOVICOL ®   Colonoscopy*   XIFAXAN ®     Supportive    Other***
                                                                                      Care**
                                  2016     €159 million   €62.2 million  €41.3 million  €12.6 million  €19.9 million

                                  2015     €159 million  €59.2 million  €34 million  €13.4 million  €34.4 million
                                                                                                                                                                                                        Workforce diversity
                                   *MOVIPREP , KLEAN-PREP , ENDOCUFF VISION ®                                                              Over 1,000 employees
                                          ®
                                                    ®
                                                         ®
                                                  ®
                                          ®
                                   **DANTRIUM , SETOFILM , MUGARD , XEROTIN ®                                                      14 sites in Europe, Australia and New Zealand                    59% women                41% men
                                   ***ZIVEREL , AXID , DESTOLIT , GIPROCOL , NORGALAX , QUADRASA , NORTUSSINE ,
                                                                      ®
                                                                               ®
                                                                                        ®
                                                     ®
                                              ®
                                          ®
                                                              ®
                                   NORMACOL , CAMCOLIT ®
                                          ®
                                                                                                                                   Norgine’s core values
                                                Direct European commercial presence
                                                             % of total product sales
                                                   NL      2
                                                 Belux       3
                                                  Apls         4
                                                Nordic           5
                                  Australia & New Zealand          6                                                                     One Norgine                 Innovation              Trustworthiness
                                                 Iberia             7
                                                  Italy             7
                                                 Other              7
                                                France                             15
                                                   UK                                 17
                                              Germany                                                   27


                                                                                                                                                                                          Dr Alastair Benbow      Philippe Caroff
                                                                                                                                                                                               appointed as         appointed as
                                                 Flexible partnerships                                                                                                                      Chief Development     VP Manufacturing
                                                                                                                                                                                             & Medical Officer       & Supply
                                                                        Norgine and its subsidiary Arc Medical Ltd
             VALEANT (NYSE: VRX and TSX: VRX)   Norgine fully acquired
               Norgine licensed PLENVU  rights to    SpePharm           licensed ENDOCUFF VISION™ rights to                        Patient centricity is key to Norgine’s future
                                    ™
                Valeant  for the US and Canada      Europe B.V.          Olympus Corporation Of The Americas
                                                                               for the US and Canada
              Norgine divested its MENA operations and product rights to Acino  Norgine continued to divest non-core products

                                            Strengthen late stage pipeline
                                                                                                                                        Over 12 million patients                 Norgine collaborated with
                                                                                  LYMPHOSEEK  ®                                     used Norgine’s key products MOVICOL ,        and provided support to
                                                                                                                                                                  ®
                                    PLENVU ®                          European Medicines Agency (EMA) approved                          MOVIPREP  and XIFAXAN ®1               26 patient organisations 2
                                                                                                                                                 ®
                         Positive Phase III programme studies –        a new LYMPHOSEEK  50 microgram kit for
                                                                                         ®
                              NOCT, MORA, and DAYB
                                                                           radiopharmaceutical preparation                         1.  XIFAXAN ®  550: COGNOS sales, (calculated assuming 130 day duration of therapy) / MOVICOL ® : 2016 actual sales, (calculated assuming 100 days of treatment on average per
                                                                                                                                     year and per patient) / MOVIPREP ® : number of procedures assuming that one patient would have one procedure per year.
                                                                                                                                   2. http://norgine.com/responsibility/transparency-public-declarations.
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